| De Hart Creek | rises in S Swain County and flows SW into Little Tennessee River. |
| De Lozier Gap | N Swain County on Welch Ridge near the head of West Fork [Chambers Creek]. |
| Dead Backwater | a sluggish body of water that flows only at high tide between Bird Island and the mainland of Colkins Neck, extending from inside Mad Inlet to Bonaparte Creek in SW Brunswick County. |
| Deaden Top | peak in central Cherokee County between Hiwassee River and West Prong Grape Creek. |
| Deadfall Creek | rises in SW Anson County and flows NE and S into South Carolina, where it enters Thompson Creek. |
| Deadline Ridge | central Clay County, extends N from Tusquitee Creek to Chestnut Branch. |
| Deals | See Wash Woods. |
| Deals Branch | rises in NW Swain County and flows S into Lake Cheoah. |
| Deals Creek | rises in N Rowan County and flows NE into Yadkin River. |
| Deals Gap | mountain gap on the Swain County, N.C.-Blount County, Tenn., line in Great Smoky Mountains National Park. Alt. 1,957. |