| Enterprise | community in E Warren County between Stonehouse Creek and Little Stonehouse Creek. |
| Enterprise | former community S of town of Mount Olive in S Wayne County. Now within town limits of Mount Olive. |
| Enterprise | community in N Davidson County. Name chosen to suggest the nature of the inhabitants. |
| Entwistle | community in central Richmond County. |
| Eoka | community in central Columbus County served by post office, 1884-1902. |
| Ephesus | community in S Davie County. Named in 1890 when a post office was est. there in Miles A. Foster's store. |
| Ephraim Branch | rises in N Haywood County and flows SW into Groundhog Creek. |
| Ephraim Hensley Mountain | N Madison County between Rick Branch and Big Creek. |
| Ephraim Place | mountain on the Mitchell County, N.C.-Unicoi County, Tenn., line. |
| Epping Forest | an eighteenth-century community and census district in SW Vance County. The community was located near the present town of Kittrell. In 1790 the district had 65 heads of families. |