| Iredell House | See James Iredell House. |
| Iredell Station | See Loray. |
| Irena | community in central Clay County on Tusquitee Creek. |
| Irene | community in SE Mecklenburg served by post office, 1871-80. |
| Irish Buffalo Creek | rises in SW Rowan County and flows S into Cabarrus County, where it enters Coldwater Creek. Called Buffalo Creek on the Collet map, 1770, but Irish Buffalo Creek on the Price map, 1808. Named for Scots-Irish settlers. See also Dutch Buffalo Creek. |
| Irish Creek | rises in W Burke County and flows SE to join Upper Creek in forming Warrior Fork [Catawba River]. |
| Irisquoque | See Clubfoot Creek. |
| Iron Duff | community in central Haywood County on Big Branch. Named for an early settler, Aaron MacDuff. Known as Aaron Duff until 1873, when a post office was est. An error in Washington, D.C., resulted in the use of the name Iron Duff instead of Aaron Duff. |
| Iron Duff Township | central Haywood County. |
| Iron Mountain | NW Mitchell County at the head of Bearwallow Creek. |