| Run of the Mill Pond | a stream that rises in SE Duplin County and flows N into Jump and Run Branch. |
| Run Swamp Canal | rises in W Currituck County and flows SE into Indiantown Creek. It forms a part of the boundary between Camden and Currituck Counties. |
| Runaway Knob | on the SE end of Runaway Ridge in SW Macon County. |
| Runaway Ridge | SW Macon County between the head of Allison Creek and the head of Ash Flat Branch. |
| Runion | community in W Madison County on French Broad River approx. 3 mi. E of Hot Springs. |
| Running Creek | rises in W Stanly County and flows NE into Big Bear Creek. |
| Runnymede | former town in central Edgecombe County. Inc. 1907 as the site of the county fair; charter repealed 1909. The site is now within the limits of Tarboro, and the name survives only as the name of a mill. |
| Runyon Creek | is formed by the junction of several small unnamed streams NE of Washington, W Beaufort County, and flows S into Pamlico River. |
| Runyon Creek | rises in N Haywood County and flows SW into Pigeon River. |
| Runyon Gap | N Haywood County on Snowbird Creek. |