| Samuel | community in SE Surry County served by post office, 1894-1905. |
| Samuel Creek | See Hayward Creek. |
| Sanatorium | See McCain. |
| Sand Branch | rises in SE Buncombe County and flows S into Broad River. |
| Sand Creek | rises in SE Granville County and flows N into Tar River. |
| Sand Flat Mountain | N Henderson County between Garren Mountain and Hooper Creek. |
| Sand Hill | community in central Buncombe County served by post office, 1873-74. |
| Sand Hill Cove | E Pender County on Northeast Cape Fear River. |
| Sand Hill Creek | rises in E central Brunswick County and flows NE into Cape Fear River. |
| Sand Hill Township | E Lenoir County. |