| Sevenmile Swamp | rises in NW Sampson County and flows SE into Great Coharie Creek. |
| Seventy-First Township | W Cumberland County. Named for the 71st Highland Scots Regiment. |
| Severn | town in NE Northampton County served by post office, 1889-1939. Alt. 59. Settled about 1833 and known first as Meherrin for an Indian tribe that had lived in the vicinity. Inc. 1919. Named for Severn Ayers, a stockholder in the Seaboard Air Line Railroad. |
| Sevier | community in N McDowell County on North Fork [Catawba River]. Served by post office, 1892-1903. Alt. 1,401. |
| Seward | community in W Forsyth County. |
| Sexton | community in S Madison County on Bull Creek. Served by post office, 1892-1905. |
| Sexton's Branch | rises in NE Wake County and flows SE into Upper Bartons Creek. |
| Seymour Johnson Air Force Base | central Wayne County at Goldsboro. Est. 1941 as an Army Air Forces Technical Training School and named for Lt. Seymour Johnson (1904-41), Navy test pilot from Goldsboro. |
| Shacklefoot Island | See Brown's Island. |
| Shackleford Banks | one of the Outer Banks, SE Carteret County; approx. 8½ mi. long. Named for John Shackle ford, who, with Enoch Ward, purchased the "Sea Banks" in 1713. See also Cape Lookout National Seashore. |