| Sassafras Branch | rises in W Jackson County and flows N into Savannah Creek. |
| Sassafras Creek | rises in E central Avery County and flows S into Lost Cove Creek. |
| Sassafras Creek | rises in SW Graham County in the Snowbird Mountains and flows NE into Snowbird Creek. |
| Sassafras Falls | in Sassafras Creek, SW Graham County. Water drops approx. 70 ft. |
| Sassafras Fork | See Stovall. |
| Sassafras Fork Township | NE Granville County. |
| Sassafras Gap | central Buncombe County E of Buzzard Rock. |
| Sassafras Gap | on the Graham-Swain county line between Cheoah Bald and Swim Bald in Nantahala National Forest. Alt. approx. 4,380. |
| Sassafras Gap | on Laurel Mountain W of Johnson Knob in NW Henderson County near the Transylvania County line. Alt. approx. 4,060. |
| Sassafras Gap | in E Jackson County on Old Bald Ridge. |